Dale Shuster Selected Research

Giant Cell Tumor of Tendon Sheath

11/2021	Exposure-response analysis of efficacy and safety for pexidartinib in patients with tenosynovial giant cell tumor.
8/2021	Pexidartinib improves physical functioning and stiffness in patients with tenosynovial giant cell tumor: results from the ENLIVEN randomized clinical trial.
1/2021	Population Pharmacokinetic Analysis of Pexidartinib in Healthy Subjects and Patients With Tenosynovial Giant Cell Tumor or Other Solid Tumors.

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Dale Shuster Research Topics

Disease

3	Giant Cell Tumor of Tendon Sheath 11/2021 - 01/2021
3	Neoplasms (Cancer) 08/2021 - 11/2016
3	Neutropenia 01/2018 - 01/2012
3	Hepatocellular Carcinoma (Hepatoma) 01/2018 - 11/2016
2	Disease Progression 01/2018 - 08/2015
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 08/2015 - 01/2012
1	Body Weight (Weight, Body) 01/2021
1	Febrile Neutropenia 01/2018
1	Ascites 01/2018
1	Fibrosis (Cirrhosis) 01/2018
1	Abdominal Pain (Pain, Abdominal) 01/2018
1	Liver Failure 01/2018
1	Sepsis (Septicemia) 01/2018
1	Acute Coronary Syndrome 01/2018
1	Acute Kidney Injury (Acute Renal Failure) 01/2018
1	Fatigue 01/2012
1	Alopecia (Baldness) 01/2012
1	Nausea 01/2012
1	Anemia 01/2012

Drug/Important Bio-Agent (IBA)

5	ARQ 197IBA 01/2018 - 08/2015
3	pexidartinibIBA 11/2021 - 01/2021
2	Sorafenib (BAY 43-9006)FDA Link 01/2018 - 11/2016
2	Erlotinib Hydrochloride (CP 358,774)FDA Link 01/2018 - 08/2015
2	Biomarkers (Surrogate Marker)IBA 01/2018 - 11/2016
1	Phosphotransferases (Kinase)IBA 01/2021
1	Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA 11/2016
1	alpha-Fetoproteins (alpha-Fetoprotein)IBA 11/2016
1	Methylnitronitrosoguanidine (MNNG)IBA 11/2016
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 11/2016
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2016
1	PlatinumIBA 08/2015
1	eribulin FDA Link 01/2012
1	Pharmaceutical PreparationsIBA 01/2012
1	taxaneIBA 01/2012

Therapy/Procedure

1	Therapeutics 01/2018